Worm gene name: |
apl-1
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Worm sequence name: |
C42D8.8
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Related human gene: |
APLP1
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Associated human disease: |
Alzheimer disease
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People involved in this project: |
- Xin Wen, California State University, Los Angeles, CA
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Left primer sequence: |
gtgatgaaggagtggggaga
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Right primer sequence: |
cgatgaataacggttggctt
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Size of PCR product: |
454
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Brief description: |
This gene encodes an almost identical isoform orthologous to human APLP-1, the overexpression of which may cause abnormal locomotion, infertility, and partial lethality.
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Report any problems that might have appeared and any solutions: |
The above abnormalities may be observed in the worms due to the overexpressed APL-1, which hopefully can be inhibited by introducing RNAi feeding bacteria.
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