| Worm gene name: |
apl-1
|
| Worm sequence name: |
C42D8.8
|
| Related human gene: |
APLP1
|
| Associated human disease: |
Alzheimer disease
|
| People involved in this project: |
- Xin Wen, California State University, Los Angeles, CA
|
| Left primer sequence: |
gtgatgaaggagtggggaga
|
| Right primer sequence: |
cgatgaataacggttggctt
|
| Size of PCR product: |
454
|
| Brief description: |
This gene encodes an almost identical isoform orthologous to human APLP-1, the overexpression of which may cause abnormal locomotion, infertility, and partial lethality.
|
| Report any problems that might have appeared and any solutions: |
The above abnormalities may be observed in the worms due to the overexpressed APL-1, which hopefully can be inhibited by introducing RNAi feeding bacteria.
|